What are the side effects of Combigan?

You may experience side effects of Combigan (brimonidine, plus timolol maleate ophthalmic solution). Some of these include:

  • dry eyes
  • blurred vision
  • headaches
  • cough
  • minor stinging, itching or burning of the eye
  • excessive tearing
  • sensitivity to light
  • dizziness
  • cough
  • increased tear production
  • feeling that something is in the eye
  • drowsiness
  • weakness
  • nausea, upset stomach, loss of appetite
  • diarrhea
  • cough or stuffy nose

If these symptoms do not go away, call your doctor.

You may experience more serious side effects.  If these occur, you will need to be seen by your doctor right away. These symptoms may include:

  • vision changes
  • eyelid swelling, scaling, pain, redness or drooping
  • eye redness, irritation, discharge, discomfort or sensitivity to light
  • drainage, crusting or oozing of eyes or eyelids
  • skin rash
  • numbness, coldness or tingling of the hands or feet
  • persistent or severe headaches
  • rapid weight gain
  • swelling of the feet, ankles or hands
  • more shortness of breath than usual
  • anxiety
  • depression

Although rare, severe symptoms and allergic reactions can occur. If you have these symptoms, this is a medical emergency. Call 911. These symptoms may include symptoms of a severe allergic reaction, such as chest tightness, trouble breathing and swelling of the tongue, face, lips or mouth as well as the following:

  • confusion
  • fainting
  • chest pain or discomfort
  • wheezing, gasping, or difficulty breathing problems
  • slow or uneven heart rate
  • pain, weakness, tingling, or numbness, especially of an arm or leg

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.