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What is physostigmine injection?

Physostigmine injection is an injectable cholinesterase inhibitor, originally sold under the brand name Antilirium. It has been used to as an antidote for harmful anticholinergic effects of drugs and plant products which cause anticholinergic toxicity, particularly in overdose situations. These drugs and plants include: atropine, scopolamine, doxepin, biperiden, nortriptyline, jimsonweed, locoweed and stinkweed. These plants and drugs can cause a dangerous condition called anticholinergic syndrome. The symptoms of this syndrome may include delirium, severe agitation, hyperthermia (increased body temperature), seizures, prolonged sleepiness and severe fast heart rate.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.