What other drugs should I mention before using apraclonidine?

If you are taking apraclonidine, tell your doctor or pharmacist if you are taking:

  • monoamine oxidase inhibitors, such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam) or tranylcypromine (Parnate). If you have used these drugs within 14 days, do not use apraclonidine.
  • other eye medications, unless prescribed by your doctor.
  • central nervous system depressant drugs, including alcohol, narcotics, barbiturates and sedatives. These drugs add to the dizziness that you might feel from taking apraclonidine.
  • beta blockers used to lower high blood pressure. Apraclonidine may add to their effects. If you are taking these drugs, your blood pressure should be checked regularly while taking apraclonidine.
  • tricyclic antidepressants, including amitriptyline, desipiramine (Norpramin), imipramine (Tofranil) and others. These drugs may prevent apraclonidine from working.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.