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How does Combigan interact with other medicines or food?

Combigan (brimonidine, plus timolol maleate ophthalmic solution) can interact with some medications. Let your doctor know if you are using any other medications, particularly calcium channel blockers, bupivacaine, certain antiarrythmics, reserpine, cimetidine, ketanserin, furazolidone, monoamine oxidase inhibitors (MAOIs) or selective serotonin reuptake inhibitors (SSRIs), since severe heart problems or low blood pressure can happen. In addition, inform your doctor if you are taking clonidine, since high blood pressure can happen; tricyclic antidepressants, since they can lower the effectiveness of Combigan; insulin or oral antidiabetics, which can increase the risk of low blood sugar; alpha-blockers, oral beta-blockers or other beta-blocker eye drops, since Combigan can raise the risks of their side effects; certain sympathomimetics, epinephrine or theophylline, since Combigan can decrease their effectiveness.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.