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What should I know about brimonidine before using it?

Brimonidine should not be used if you currently take isocarboxazid, phenelzine, selegiline, tranylcypromine or other monoamine oxidase inhibitor drugs. Brimonidine can also interact with antidepressants amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline and trimipramine; guanethidine; furazolidone; the barbiturates phenobarbital and secobarbital; bromocriptine; digoxin; ergotamine; methyldopa; selegiline; sedatives; catechol-O-methyltransferase inhibitor drugs; sleeping pills; tranquilizers; and drugs used to treat anxiety, high blood pressure, mental illness, pain or seizures.

Discuss possible drug interactions with your doctor before using brimonidine. Certain medical conditions should be considered before using brimonidine, including depression; heart, kidney or liver disease; low blood pressure; poor circulation in the hands or feet; and Raynaud's disease. Pregnant or breastfeeding women should discuss the risks and benefits of brimonidine. If you wear soft contact lenses, remove them before using brimonidine and wait at least 15 minutes before putting them back in your eyes.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.