Do itraconazole capsules interact with other medications?

Yes, itraconazole (Sporanox), an antifungal drug, can interact with:
  • antacids and stomach acid reducers (they can lower your body's ability to absorb itraconazole)
  • other antifungals
  • antibiotics
  • antidepressants and anxiety medications
  • anti-rejection drugs for organ transplants
  • barbiturates
  • blood thinners
  • oral diabetes medications
  • sedatives
  • sleep aids
  • medications for blood pressure, cancer, cholesterol, heart, HIV/AIDS, seizures or tuberculosis
You should not take itraconazole along with the following drugs:
  • methadone
  • disopyramide
  • dofetilide
  • dronedarone
  • quinidine
  • ergot alkaloids, such as dihydroergotamine, ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine)
  • irinotecan
  • lurasidone
  • oral midazolam
  • pimozide
  • triazolam
  • felodipine
  • nisoldipine
  • ranolazine
  • eplerenone
  • cisapride
  • lovastatin
  • simvastatin
  • colchicine
Tell your doctor about all of the drugs (over-the-counter and prescription) and supplements that you take.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.