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How does Flucytosine work?

Flucytosine is an antifungal medicine. It works by slowing the growth of certain types of fungal infections. This drug is also known as 5-fluorocytosine or “5-FC.” On its own, 5-FC doesn’t have antifungal benefits. But when absorbed by fungal cells, it changes into another drug. This is called 5-fluorouracil (5-FU). This drug actually changes the chemistry of the fungus. Flucytosine is usually taken with other medicines. Typically, it’s combined with another antifungal called amphotericin B.

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