What are the side effects of droperidol?

Droperidol produces side effects in several of the body's systems. Effects on the cardiovascular system include: prolonged QT interval (an EKG abnormality), abnormal heart rhythm, cardiac arrest, palpitations and fainting. Other problems include a mild-to- moderate decrease in blood pressure or an increase in heart rate. When combined with the drug fentanyl, an increase in blood pressure may occur. The neurologic side effects include: drowsiness, restlessness (akathisia), dystonia (impairment of muscle tone), hyperactivity and anxiety. Some people experience hallucinations, temporary mental depression and oculogyric crisis (a temporary inability to move the eyes from a fixed position). Respiratory side effects include: laryngospasm, bronchospasm and respiratory depression. In addition, there are also some miscellaneous side effects, including rigid muscles, shaking and chills. Rare cases of neuroleptic malignant syndrome have been reported. This results in altered consciousness, autonomic instability and muscle rigidity.

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