How soon after taking metoclopramide will my symptoms improve?

You need to take metoclopramide as directed by your doctor for it to work properly. The number of daily doses, the time interval between doses, and the duration of treatment depend on the medical issue for which you are being treated. If you are taking metoclopramide for gastroesophageal reflux disease (GERD), it might be a few days to weeks for the medication to work, but do not stop taking it without consulting your doctor. If you are taking the medication for slow emptying of the stomach due to diabetes, your symptoms will not improve immediately. Your nausea and vomiting might  start to subside soon after beginning treatment - and continue to subside over the next three weeks, but it might take longer for the feeling that you are full to leave.

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