What should I know about aprepitant capsules before taking them?

Before taking aprepitant capsules you should know that it can interact with many medications. Taking Aprepitant with pimozide may cause life-threatening side effects.

Before taking aprepitant capsules, tell your doctor if you are taking any of the following drugs:

  • tolbutamide; warfarin or other blood thinner; midazolam; Valium; Xanax; Tranxene;
  • antidepressants such as nefazodone or paroxetine; antibiotics such as clarithromycin or rifampin;
  • antifungals such as itraconazole or ketoconazole; cancer medications such as ifosfamide,
  • vinblastine, or vincristine; HIV drugs such as nelfinavir, lopinavir/ritonavir, or ritonavir;
  • seizure medicines such as carbamazepine or phenytoin; or steroid drugs such as dexamethasone or methylprednisolone.

Aprepitant may also reduce effectiveness of hormonal birth control methods, so you should also use a condom or other barrier contraceptive for a month after you take aprepitant.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.