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How does metoclopramide treat GERD?

Metoclopramide is used to treat gastroesophageal reflux disease (GERD) in individuals for whom other therapy does not work. Metoclopramide is a gastrointestinal stimulant, as well as an antinausea agent. It works by blocking a chemical in the brain and by increasing the muscle contractions of the upper digestive tract. This helps speed up the time it takes the stomach to empty into the intestines. It also works in specific brain areas to reduce nausea.

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