How does droperidol interact with other drugs or foods?

Droperidol interacts with multiple drugs. Most interactions involve risk of excessive sedation or prolongation of the QT interval, resulting in cardiac arrhythmias, including torsades de pointes. Do not take droperidol if you are taking any of the following antibiotics: ciprofloxacin, clarithromycin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, sparfloxacin, telithromycin and troleandomycin. In addition, do not take droperidol if you are on chemotherapy drugs, such as daunorubicin or doxorubicin. Interactions also occur with chloroquine, clozapine, cyclobenzaprine, general and local anesthetics, halofantrine and haloperidol. Use of droperidol with these following medications is not recommended: acetophenazine, bepridil, bromperidol, clozapine, dronedarone, levomethadyl, mesoridazine, molindone, perphenazine, pimozide, and pipamperone, remoxipride, thioridazine, tiaprid, triflupromazine and ziprasidone. In general, drugs known to cause cardiac arrhythmias by prolonging the QT interval, antimalarials, antidepressants, certain antihistamines and calcium channel blockers, should not be used concurrently with droperidol. Also, if a person is taking barbiturates, tranquilizers, general anesthetics or opioids, that person has an increased risk of excessive sedation. In addition, if a person is taking medications that cause low potassium or magnesium levels, they are at risk for prolongation of the QT interval.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.