How does Aloxi interact with other medications or foods?

Aloxi (palonosetron) interacts with many medications. For example, when taken with apomorphine Aloxi can cause an unsafe drop in blood pressure that can result in fainting. Taking Aloxi with other drugs that increase serotonin in the brain, such as antidepressants and migraine medications, can lead to a dangerous condition called serotonin syndrome. Taking Aloxi along with water pills (diuretics) or heart rhythm drugs (including, amiodarone, bepridil, disopyramide, sotalol) may also pose problems. Tell your doctor about all prescription and over-the-counter (OTC) drugs and supplements you take before starting treatment. There are no known interactions between Aloxi and food.

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