What should I know about difenoxin and atropine?

Before taking the combination drug difenoxin and atropine, also known by the brand name Motofen, you should know that difenoxin can be habit-forming when taken above a certain dose. Atropine was added to this medication to prevent its abuse, because it will cause unpleasant side effects if you take too high of a dose. You should tell your doctor if you have ulcerative colitis, liver disease or diarrhea due to certain types of infections, such as pseudomembranous colitis following recent antibiotic therapy or a bacterial infection of the gut caused by E. coli, salmonella, or shigella, before taking Motofen.