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Who should not take diphenoxylate and atropine?

You should not use diphenoxylate and atropine (Lomotil) if your diarrhea is caused by food poisoning or certain other medical conditions, such as colitis. If you currently have jaundice or if you are taking sodium oxybate, you should not be using Lomotil.

Certain health problems would also prevent you from being able to safely take this medication, including stomach or bowel blockages, myasthenia gravis, heart conditions that involve bleeding, too much stomach acid, weakness of the intestinal muscles, problems swallowing, glaucoma or a blockage of the urinary tract.

Talk to your doctor if you have abnormal electrolyte levels, nerve damage, Down syndrome, ulcerative colitis, liver or kidney problems, asthma, a hernia, open-angle glaucoma, any heart condition, difficulty urinating, any prostate problem, a bladder blockage or dehydration.

You should also not use the medication if you are nursing because atropine can be passed to the baby through breast milk.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.