Who should not take Glucovance?

Women who are pregnant or breastfeeding should not take Glucovance (glyburide and metformin), a combination diabetes drug. If women can't control their blood sugar levels with diet and exercise, doctors often recommend insulin during pregnancy instead. People who have kidney or liver disease should also not take Glucovance -- and because kidney function often declines with age, people over the age of 80 should not use Glucovance before taking a kidney test. People with heart failure, diabetic ketoacidosis or glucose-6-phosphate dehydrogenase deficiency should not take the medication.

Anyone who drinks alcohol in excess, either on a regular basis or in occasional binges, should not take Glucovance, because the combination raises the risk of developing low blood sugar (hypoglycemia) and a rare but serious side effect called lactic acidosis. People who need surgery should stop taking Glucovance beforehand; ask your doctor about alternative ways to control your blood sugar until after the operation. Finally, you should not take Glucovance if you're allergic to glyburide, metformin or any other ingredients of the drug.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.