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What are possible side effects of Glucovance?

The most common side effects of Glucovance (glyburide and metformin), a combination drug for type 2 diabetes, include diarrhea, headache, upper respiratory infection, nausea or vomiting, abdominal pain and dizziness. In clinical trials, each of these symptoms occurred more than 5% of the time. Rare but more serious side effects include those caused by low blood sugar (hypoglycemia). Signs of low blood sugar include:
  • dizziness
  • shakiness
  • sweating
  • hunger
  • seizure
  • coma
Like many other diabetes medications, Glucovance can cause hypoglycemia, or low blood sugar. Hypoglycemia can be dangerous, leading to confusion, seizures or loss of consciousness. Earlier signs include:
  • light-headedness
  • dizziness
  • shakiness
  • sweating
  • nervousness
  • irritability
  • weakness
Rarely, Glucovance can also cause a serious condition known as lactic acidosis. Call your doctor right away if you have symptoms of lactic acidosis, including:
  • general uneasiness or discomfort
  • trouble breathing
  • muscle pain
  • sleepiness
  • stomach pain or discomfort
  • high blood pressure
  • feeling cold
  • irregular heartbeat

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.