What is the proper dose of glibenclamide?

Glibenclamide (called glyburide in the US) is taken to treat type 2 diabetes. With this condition, insulin is not secreted in enough quantity for it to be used properly in the body. This drug increases insulin secretion from the pancreas. It then helps the body use insulin effectively. Typical adult dosage guidelines are:
  • The standard initial dose is 2.5 milligrams (mg.) taken orally (by mouth), once a day. It’s taken in the morning with food.
  • The standard maintenance dose is 1.25 to 20 mg. orally, in one or two divided doses.
  • The standard maximum dose is 20 mg. per day.

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