Advertisement

What should I know about glyburide and metformin before taking it?

Before you take glyburide and metformin (brand name: Glucovance), a combination drug for type 2 diabetes, you should know that it can cause a rare but potentially life-threatening reaction called lactic acidosis, a toxic buildup of lactic acid in the blood. Your risks for lactic acidosis may be higher if you have a history of kidney, liver or heart problems, so your doctor should make sure these organs are working well enough to handle this drug. Your risk also goes up if you drink large amounts of alcohol or are 80 years of age or older.

Before you take glyburide and metformin, you should also know how to respond to low blood sugar (hypoglycemia) because that sometimes occurs in people who are on this drug.

Continue Learning about Antidiabetic

What is exenatide for diabetes?
American Diabetes AssociationAmerican Diabetes Association
Exenatide (brand name Byetta) is the first in a new class of drugs for the treatment of type 2 diabe...
More Answers
Does liraglutide interact with any other medications?
Donna Hill Howes, RNDonna Hill Howes, RN
Liraglutide can affect the absorption of some oral medications; it is important that the healthcare ...
More Answers
How much insulin do I need per gram of carbohydrate?
Toby SmithsonToby Smithson
The insulin to carbohydrate (I:C) equation takes into account the amount of 1 unit of rapid active i...
More Answers
What is Novolin?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Novolin (insulin human) is a form of man-made insulin -- a hormone normally produced in the panc...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.