What is Janumet?

Janumet (combination metformin and sitagliptin) is a type 2 diabetes medication that works by lowering blood sugar and regulating insulin. Specifically, metformin helps to reduce production of glucose (sugar) in the liver, to reduce glucose absorption in the intestines, and to enhance the ability of cells to use sugar more effectively. Sitagliptin helps the pancreas to release more insulin and signals the liver to stop producing glucose when blood sugar levels are too high. Janumet is an oral medication specifically for use in persons with type 2 diabetes. It should not be used by persons with type 1 diabetes, as type 1 diabetes indicates that the body is unable to produce and regulate its own insulin levels and therefore requires a different type of treatment.

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