What is the difference between Metformin HCL and Metformin ER?

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  • A answered

    Metformin HCL and Metformin ER contain the same active ingredient, metformin. Metformin HCL is an immediate-release formulation of metformin.  It is taken multiple times each day.  Metformin ER is an extended-release formulation of metformin.  It can usually be taken once a day. 

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