Advertisement

What are the side effects of Actos (pioglitazone)?

Actos (pioglitazone) does not cause low blood sugar, but low blood sugar may occur when it is taken with other diabetes medicines. Your doctor should instruct you about what to do if you experience low blood sugar. Symptoms may include shakiness, sweating, irritability, weakness, and pale skin. 

Another possible side effect is high blood sugar. See medical help if you experience the symptoms of high blood sugar, including extreme hunger or thirst, blurred vision, and frequent urination. If high blood sugar goes untreated, it can develop into diabetic ketoacidosis, which is a life-threatening condition. 

Additional possible side effects of Actos are listed below. If you experience any of these to a severe degree or if they do not go away, tell your doctor: 
-headache
-runny nose and other cold
-like symptoms
-muscle pain
-sore throat
-tooth or mouth pain

If you experience these more serious side effects, seek medical help immediately: 
-dark urine
-yellowing of the skin or whites of the eyes
-blurred vision
-vision loss
-nausea
-vomiting
-loss of appetite
-excessive tiredness

Another possible side effect of this drug is bladder cancer. In clinical studies, those who took Actos developed this cancer at a higher rate than those who did not take the drug. Women should also be aware that women who took this drug were at higher risk for developing bone fractures than women who did not take the drug. Men did not experience the same risk. 

Continue Learning about Antidiabetic

What should I know before taking alpha-glucosidase inhibitors?
Donna Hill Howes, RNDonna Hill Howes, RN
If you are pregnant, planning to become pregnant, or may be pregnant, alpha-glucosidase inhibitors m...
More Answers
Does long-acting insulin cause less weight gain?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Long-acting insulin (such as Lantus and Levemir) and newer premixed insulin (such as Humulog 50/...
More Answers
What are alpha-glucosidase inhibitors?
Donna Hill Howes, RNDonna Hill Howes, RN
Alpha-glucosidase inhibitors slow the digestion of carbohydrates in the small intestine. Alpha-gluco...
More Answers
How do the diabetes drugs Byetta and Victoza affect weight?
Dr. Jack Merendino, MDDr. Jack Merendino, MD
Since it was introduced in 2006, Byetta has been prescribed widely. Victoza was introduced in 2010 a...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.