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Are there any risks in taking glyburide-metformin?

People who take glyburide-metformin are at risk for a rare but potentially life-threatening condition called lactic acidosis. This is caused by the metformin in this combination medicine. Your risks for lactic acidosis may be higher if you drink large amounts of alcohol; are 80 years or older; and have a history of heart, liver or kidney problems.

Glyburide-metformin increases drowsiness in some people. If you are taking this drug, use caution before you drive or operate machinery. This medicine also increases your sensitivity to sunlight. Make sure you use sun protection and avoid tanning beds. There may be some risks of unwanted side effects from taking this drug if you are pregnant. The elderly risk more serious side effects when taking this drug. Glyburide-metformin should not be used in children under nine years of age. Talk to your doctor about the risks of glyburide-metformin. They will be able to help determine whether the benefits outweigh the risks.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.