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Is it safe to use glyburide and metformin if I'm pregnant?

You should try to avoid glyburide and metformin (brand name: Glucovance) during pregnancy. This combination drug for type 2 diabetes has not been tested in animals, but when glyburide and metformin were tested separately, neither caused birth defects. However, if a woman is taking glyburide and metformin when she gives birth, her baby may be born with dangerously low blood sugar. Because of this, experts say that alternatives are a better choice during pregnancy. If you do need to take glyburide and metformin during pregnancy, your doctor will likely recommend that you stop at least two weeks before your due date.

If you are pregnant or planning to become pregnant, talk to your doctor before taking glyburide and metformin. If you are already taking glyburide and metformin and become pregnant, call your doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.