What should I know about glipizide and metformin before taking it?

Before taking glipizide and metformin, you should know some potential risks associated with this medication. In some cases, the medication may increase the risk for a condition called lactic acidosis, which involves a buildup of acid in the blood and can become life-threatening. If you develop symptoms of lactic acidosis, such as shortness of breath, light-headedness, fainting, weakness, slowed heartbeat, feeling cold, muscle or stomach pain, or unusual sleepiness, get emergency medical attention immediately. People who have liver disease, kidney disease, or congestive heart failure are at a greater risk for lactic acidosis, so tell your doctor if you have any of these conditions before taking glipizide and metformin. Your risk for this and other serious complications may also be increased if you have any X-ray or CT scans that involve a dye being injected into your veins. If you need one of those procedures while taking glipizide and metformin, talk to your doctor first because you may need to stop taking the medication temporarily.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.