Advertisement

How can pioglitazone help treat multiple sclerosis (MS)?

A small double-blind clinical trial involving patients with relapsing-remitting multiple sclerosis (MS) has indicated that a drug used to treat diabetes shows protective effects in the brain.

At the University of Illinois at Chicago (UIC) College of Medicine, trial participants were given pioglitazone, a Food and Drug Administration (FDA)-approved type 2 diabetes drug commercially known as Actos, or a placebo. They continued their normal course of therapy during the trial.

After one year, participants taking pioglitazone, which is known for its anti-inflammatory effects, had shown significantly less loss of gray matter than patients taking the placebo. A report about the study was published in an online edition of the Journal of Neuroimmunology.

A larger trial is needed to confirm these preliminary results, but in the meantime, researchers are trying to learn more about pioglitazone's protective effect on neurons.

Continue Learning about Antidiabetic

What should I know before taking pramlintide?
Donna Hill Howes, RNDonna Hill Howes, RN
If you have diabetic gastropathy, you should not take pramlintide. Pramlintide increases the risk o...
More Answers
Does liraglutide cause any side effects?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include headache, indigestion, nausea, low blood sugar, diarrhea, constipation, vom...
More Answers
If I need insulin to control my blood glucose, which type should I take?
American Diabetes AssociationAmerican Diabetes Association
Your insulin doses should mimic how insulin works naturally in the body. In people without diabetes,...
More Answers
How effective is liraglutide?
Donna Hill Howes, RNDonna Hill Howes, RN
People taking liraglutide for a year along with a program of diet and exercise lost an average of 18...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.