How does glyburide interact with other medications or foods?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner
nolol, carvedilol metoprolol, and propranolol. You are more likely to develop low blood sugar if you are taking glyburide in combination with other drugs that tend to lower blood sugar, such as certain nonsteroidal anti-inflammatory drugs, aspirin, sulfa drugs, and monoamine oxidase inhibitors.

If you are taking any drugs that inadvertently raise blood sugar, you are more likely to develop hyperglycemia, or high blood sugar, while taking glyburide. These include isoniazid, diuretics, steroids, phenothiazines, thyroid medicine, birth control pills and other hormones, heart or blood pressure medicines, seizure medicines, diet pills, and medicines used to treat asthma, the common cold, or allergies.
Other drugs that may increase the side effects related to glyburide include antibiotics; anticoagulants, or blood thinners; cyclosporine; disopyramide; fluconazole; ketoconazole; fluoxetine; rifampin; ACE inhibitors;niacin; phenytoin; and certain vitamins. You should avoid alcohol while taking this drug, as it can result in low blood sugar.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.