How does glipizide affect hypoglycemia?

Glipizide can sometimes cause hypoglycemia by lowering blood sugar levels too much. To reduce your risk of developing hypoglycemia, avoid drinking alcohol and skipping meals. Signs of hypoglycemia include dizziness, irritability, shakiness, nervousness, sudden mood swings, mouth numbness, headaches, weakness, hunger, pale skin, or poor coordination. If you experience these symptoms, you can increase blood sugar levels by eating or drinking something that includes sugar (orange juice, milk, candy, or glucose gel) or with a using glucagon injection.

Symptoms of severe, life-threatening hypoglycemia (seizure, extreme weakness, blurred vision, sweating, difficulty speaking, confusion, difficulty breathing, stomach pain and coma) require immediate medical attention.