How does the combination of repaglinide and metformin work?

Stacy Wiegman, PharmD

Pharmacy

Each of the active ingredients in repaglinide and metformin (PrandiMet) works in complementary ways to control blood sugar levels in people with type 2 diabetes in several ways. Repaglinide triggers the pancreas to produce insulin, which makes it possible for the body's cells to take in the glucose needed for energy. Metformin decreases both the production of glucose (sugar) by the liver and the absorption of glucose by the intestines.

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