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Do any other drugs interact with pramlintide?

Donna Hill Howes, RN
Family Practitioner

Because pramlintide may affect absorption rates of some oral drugs, follow instructions carefully for dose times for oral medications when taking premlintide.

If you are taking an anticholinergic agent or an alpha-glucosidase inhibitor, pramlintide may not be right for you.

Oral anti-diabetic products, angiotensin converting enzyme (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, propoxyphene, salicylates, somatostatin analogs, and sulfonamide antibiotics all may increase the susceptibility to severe hypoglycemia when taken with pramlintide. All should be taken with caution. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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