Why is there a black box warning on Pamelor?

There is a black box warning on Pamelor (nortriptyline) because some research shows that it and other antidepressants may increase the likelihood of suicidal thoughts and attempts in children, teens and adults under age 25 who take it. Pamelor is not approved by the Food and Drug Administration to treat mental illness in children; however doctors can prescribe it "off label" for children suffering from depression, panic disorder or other conditions.

You and your doctor need to weigh the Pamelor's potential benefits against its potential risks. If you or your child takes the drug, you should watch for signs of potential trouble, including worsening depression or anxiety, aggressive or reckless behavior, trouble sleeping, hostility, panic attacks, extreme agitation, irritability or impulsiveness.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.