Who should not take Pamelor?

The following people may not be good candidates for treatment with the antidepressant medication Pamelor (nortriptyline):

  • anyone who is allergic to nortriptyline or any ingredient in Pamelor
  • women who are pregnant, plan to become pregnant soon, or who are breastfeeding. More research is needed to know if Pamelor is safe for use during pregnancy and while nursing.
  • anyone who is recovering from a heart attack 
  • children. Pamelor has not been proven to be safe and effective for treating children, although a doctor may decide it's appropriate in some cases.  
  • people who have certain medical conditions, including the eye disorder glaucoma, an enlarged prostate gland (men) or trouble urinating, diabetes, epilepsy, thyroid gland problems, or liver, kidney or heart disease.
  • people diagnosed with schizophrenia
  • people scheduled to undergo surgery, including dental surgery

In addition, people who take certain medications that can interact with Pamelor may need to either stopping taking those medications or not use Pamelor. Give your doctor a list of all your other medications and supplements. It's particularly important to let your doctor know if you take:

  • other antidepressant medications called monoamine oxidase inhibitors (MAOIs), or any drug prescribed for a mental health condition
  • blood thinners, such as warfarin
  • antihistamines or other cold or allergy medications
  • cimetidine
  • flecainide 
  • guanethidine or other blood pressure medicines
  • lithium
  • seizure medications
  • drugs to treat Parkinson's disease
  • asthma medications
  • diabetes medications
  • sedatives or any drug that increases drowsiness
  • thyroid medication

Continue Learning about Antidepressant

Are Antidepressants Safe to Take During Pregnancy?
Are Antidepressants Safe to Take During Pregnancy?
Research suggests that depression is diagnosed twice as often in women as it is in men, and it typically presents during a woman’s childbearing years....
Read More
Can tricyclic antidepressants help prevent migraine headaches?
Dr. Egilius L. Spierings, MDDr. Egilius L. Spierings, MD
Tricyclic antidepressants are sometimes prescribed to treat various types of pain, including headach...
More Answers
What are the side effects of amitriptyline?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include drowsiness, agitation, dry mouth, blurred vision, urinary problems, constip...
More Answers
What Is Treatment-Resistant Depression?
What Is Treatment-Resistant Depression?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.