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When should I call my doctor if I am taking Paxil CR?

If you are taking the antidepressant Paxil CR (the extended-release formulation of paroxetine), you should call your doctor for the following reasons:
  • You are considering stopping the drug. Stopping Paxil CR suddenly may cause a worsening of depression or anxiety or other withdrawal symptoms. Your doctor may need to taper your dose slowly to prevent withdrawal symptoms. Do not stop taking Paxil CR until you talk to your doctor.
  • You have found out you are pregnant. Paxil CR may harm a developing fetus. You and your doctor should weigh Paxil CR's potential benefits to you against its possible risks to your developing fetus.
  • You are considering taking a new medication or supplement. Paxil CR can interact with certain drugs and supplements, increasing the risk of side effects or other problems. Do not start any medication or supplement while you are taking Paxil CR without checking with your doctor first.
  • You have been diagnosed with a new medical condition. Paxil CR may not be safe to take if you have certain conditions, including problems with your liver, heart or kidneys, bleeding problems, glaucoma or seizure disorders.
You should also call your doctor if you experience side effects, especially the following:
  • changes in mood or behavior, such as acting impulsively, aggressively, or violently; new or worse depression or anxiety; symptoms of mania (restlessness, agitation, fast talking, racing thoughts); suicidal thoughts or behavior
  • blurred vision
  • symptoms of serotonin syndrome (a condition in which the brain has too much of the neurotransmitter serotonin), including hallucinations, agitation, racing heartbeat, high or low blood pressure, sweating or fever, vomiting or diarrhea, coordination problems, muscle stiffness or twitching
  • signs of allergic reaction, including trouble breathing, hives or skin rash, fever, joint pain, swelling of the face, tongue, eyes or mouth
  • abnormal bleeding, especially if you also take blood thinners or non-steroidal anti-inflammatory drugs, such as ibuprofen, naproxen or aspirin
  • seizures or convulsions
  • symptoms of low sodium levels in the blood (more common in elderly people who take Paxil CR), including headache, weakness or feeling unsteady, confusion, trouble concentrating, memory problems
  • trouble urinating or changes in frequency of urination
  • numbness, tingling or burning pain in your hands, arms, feet or legs

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.