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What are possible side effects of tricyclic antidepressants?

Donna Hill Howes, RN
Family Practitioner

Side effects may include dry mucous membranes, blurred vision, constipation, and trouble urinating. These drugs may also cause drowsiness, agitation, sudden drops in blood pressure upon standing, a rapid or slowed heartbeat, and changes in blood sugar. Men may have a change in sex drive, erection problems, or problems reaching orgasm.

Tricyclic antidepressants can make it dangerous to drive or operate machinery. Some people, especially younger people, may have suicidal thoughts or behavior. 

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Side effects of tricyclic antidepressants can include dry mouth, blurred vision, dizziness, increased appetite, weight gain, constipation, and difficulty urinating. People with a history of glaucoma, heart disease, or an enlarged prostate should avoid these drugs.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.