Advertisement

What are side effects of selective serotonin reuptake inhibitors (SSRIs)?

Selective serotonin reuptake inhibitors (SSRIs) are the most common medication for major depression. "These are the first choice because they have more benign side effects," says William Marchand, MD, assistant professor of psychiatry at the University of Utah. SSRI side effects include loss of interest in sex, difficulty achieving orgasm, anxiety, sleep problems, and loss of appetite. Most side effects will go away after a short time. If not, your doctor may try another drug. Keep in mind, SSRIs may not be safe if you're pregnant or trying to become pregnant.

Kent Holtorf, MD
Endocrinology Diabetes & Metabolism
The most common class of antidepressants called SSRIs (selective serotonin reuptake inhibitors), which include Prozac, Zoloft, Lexapro and Celexa, are shown to significantly increase the risk of diabetes and double the rate of bone loss.

Continue Learning about Antidepressant

Are Antidepressants Safe to Take During Pregnancy?
Are Antidepressants Safe to Take During Pregnancy?
Research suggests that depression is diagnosed twice as often in women as it is in men, and it typically presents during a woman’s childbearing years....
Read More
How safe are sedating antidepressants for people with dementia?
Sarah N. Mourra, MDSarah N. Mourra, MD
Oftentimes, doctors will use sedating antidepressants for sleep issues in people with dementia. A ve...
More Answers
Can I have a good sex life if I'm on antidepressants?
Jan L. Shifren, MDJan L. Shifren, MD
You don't need to sacrifice your sex life in order to treat depression. Some newer antidepressan...
More Answers
What Is Treatment-Resistant Depression?
What Is Treatment-Resistant Depression?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.