What is Savella used for?

Savella (milnacipran) is a medication prescribed to treat fibromyalgia. It belongs to a class of drugs called selective serotonin-norepinephrine reuptake inhibitors (SNRIs), most of which are approved to treat depression. People with fibromyalgia typically have ongoing pain, muscle stiffness and tenderness, tiredness and trouble sleeping. Savella and other SNRIs work by boosting the brain chemicals serotonin and norepinephrine, which suppress pain signals and help regulate mood.

Because Savella is chemically similar to drugs used for depression, people taking this medicine must be careful to watch for side effects that can occur with certain antidepressants -- most dangerously an increase in suicidal thoughts and actions among young adults, adolescents and children.

Continue Learning about Antidepressant

Are Antidepressants Safe to Take During Pregnancy?
Are Antidepressants Safe to Take During Pregnancy?
Research suggests that depression is diagnosed twice as often in women as it is in men, and it typically presents during a woman’s childbearing years....
Read More
How effective is nortriptyline for quitting smoking?
Donna Hill Howes, RNDonna Hill Howes, RN
Studies show nortriptyline is about as effective as bupropion or nicotine replacement therapy, but n...
More Answers
How effective are antidepressants for treating hot flashes?
Univ. of Nev. School of Medicine, Family MedicineUniv. of Nev. School of Medicine, Family Medicine
The effectiveness of antidepressants for treating hot flashes is variable. Some women experience com...
More Answers
What Is Treatment-Resistant Depression?
What Is Treatment-Resistant Depression?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.