What is Savella used for?

Savella (milnacipran) is a medication prescribed to treat fibromyalgia. It belongs to a class of drugs called selective serotonin-norepinephrine reuptake inhibitors (SNRIs), most of which are approved to treat depression. People with fibromyalgia typically have ongoing pain, muscle stiffness and tenderness, tiredness and trouble sleeping. Savella and other SNRIs work by boosting the brain chemicals serotonin and norepinephrine, which suppress pain signals and help regulate mood.

Because Savella is chemically similar to drugs used for depression, people taking this medicine must be careful to watch for side effects that can occur with certain antidepressants -- most dangerously an increase in suicidal thoughts and actions among young adults, adolescents and children.

Continue Learning about Antidepressant

Are Antidepressants Safe to Take During Pregnancy?
Are Antidepressants Safe to Take During Pregnancy?
Research suggests that depression is diagnosed twice as often in women as it is in men, and it typically presents during a woman’s childbearing years....
Read More
What are possible side effects of tricyclic antidepressants?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include dry mucous membranes, blurred vision, constipation, and trouble urinating. ...
More Answers
What medications should I avoid if I take antidepressants?
John Preston, PsyDJohn Preston, PsyD
Interactions between antidepressants and other medications vary depending on the antidepressant. The...
More Answers
What Is Treatment-Resistant Depression?
What Is Treatment-Resistant Depression?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.