What are possible side effects of Nardil?

Common side effects of the antidepressant medication Nardil (phenelzine) tend to be mild and improve as treatment continues or if your doctor adjusts your dose. These side effects may include:

• dry mouth
• headache
• dizziness or lightheadedness
• changes in sleep (insomnia or sleeping more)
• fatigue
• weakness
• twitching, jerking or other involuntary movements
• constipation, nausea or vomiting
• weight gain
• changes in sex drive or ability

Other side effects of taking Nardil are less common but may be serious. These include nausea or vomiting. In some cases, headache and sleep problems may also indicate a serious problem. Call your doctor immediately if you experience a side effect that bothers you, or if you experience any of the following: 

• sudden or severe changes in mood or behavior, including new or worsened depression, anxiety, suicidal thoughts or attempts, aggressiveness, restlessness and insomnia
• signs of allergic reaction, including skin itching or hives, chest tightness, trouble breathing, or swelling of face, hands, mouth or throat
• eye pain, vision changes or sensitivity to bright light
• fast, slow or pounding heartbeat
• fevers, chills, sweating, sore throat or body aches
• headaches in the back of your head
• problems urinating
• yellowing of your skin or whites of your eyes
• stiff or sore neck
• seizures or tremors

Nardil may interact with medicines and certain foods, increasing your risk of side effects. Ask your doctor for a list of foods that you should avoid (which may include alcohol, caffeine, and anything fermented, pickled, aged or smoked). Before starting Nardil, give your doctor a list of all your medications (prescription and over-the-counter) and dietary and herbal supplements. Once you're on Nardil, do not take any new medicine or supplement without consulting your doctor first.