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What should I know before my child uses Tofranil?

Before giving your child Tofranil (imipramine), you should know that the Food and Drug Administration (FDA) has approved it only for use in children to treat bedwetting, and only for kids over 6. However, it's sometimes prescribed for children for other conditions, including depression. Once a drug is FDA approved, doctors can prescribe it to anyone for any condition, a practice known as off-label use.

If your doctor suggests Tofranil to treat your child’s depression or bedwetting, you should know that this drug, like other antidepressants, may increase the risk of suicidal thoughts in children and young adults. If, after carefully weighing the risks and benefits of treatment with your doctor, you decide to proceed, be sure to carefully monitor your child for side effects, including increased irritability, agitation and unusual changes in behavior or mood.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.