What is the most important information I should know about trimipramine?

Trimipramine, like other antidepressant medications, may increase the risk for suicidal thoughts and behavior, especially in children, teenagers, and young adults. A person with increased suicidal tendencies may be more anxious, restless, hostile, or irritable, and may act impulsively or suffer panic attacks. Talk to your doctor immediately if you notice any changes in mood of a person taking trimipramine.

Do not take trimipramine if you have a recent history of heart attack or have taken a monoamine oxidase inhibitor (MAOI) within the last two weeks. Trimipramine may not be suitable for people with kidney disease, hyperthyroidism, diabetes, or glaucoma.
Trimipramine may make your skin more sensitive to sunlight, so use sunscreen and wear protective clothing outside.
Avoid alcohol and other medications that can cause drowsiness while taking trimipramine. Do not drink grapefruit juice or eat grapefruit while taking trimipramine, as trimipramine may interact with these foods.

Do not suddenly stop taking trimipramine. To avoid withdrawal symptoms, talk to your doctor about how to wean yourself off trimipramine by decreasing your dose each time you take it.
Before taking trimipramine, tell your doctor all prescription medications, over-the-counter medications, vitamins, and herbal supplements you are taking. Be sure to include any medications that may interact with trimipramine, including certain antidepressants, heart rhythm medications, cimitedine, and guanethidine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.