Can Nardil interact with other medications or foods?

Nardil (phenelzine), an antidepressant medication, may interact with a number of other medications or foods, and those interactions can sometimes be dangerous. Before you start taking Nardil, give your doctor a list of all your medications (prescription and over-the-counter) and supplements. Be especially careful to let your doctor know if you take any of the following:
  • other antidepressants or any medication for a mental health issue
  • cold and cough medicines (especially those that contain dextromethorphan)
  • decongestants (pills, drops or sprays) or sinus medications
  • hay fever medications
  • asthma inhalants
  • drugs to control appetite or reduce weight
  • caffeine or other stimulants
  • tryptophan
  • blood pressure medicine
  • narcotics, sedatives or any drug that makes you sleepy, including anesthesia used for surgery
  • insulin or other diabetes medications

Once you start taking Nardil, do not take any new medication or supplement without consulting your doctor first.

Your doctor will probably give you a list of foods that you should avoid completely or consume only minimally while you are taking Nardil. Some foods contain substances that can interact with Nardil. Eating the wrong food while you're on this drug can cause spikes in blood pressure that could lead to stroke. Your doctor may tell you to avoid foods that are pickled, aged, fermented or smoked. Here's a partial list of foods and beverages to avoid:
  • pickled herring
  • liver
  • salami, pepperoni and Lebanon bologna
  • fava bean pods
  • sauerkraut
  • cheese (except for cottage or cream cheese)
  • yogurt
  • alcohol, including beer, wine and reduced alcohol or alcohol-free versions of beer and wine
  • excessive amounts of chocolate
  • eyeast or meat extracts, or brewer's yeast
Talk to your doctor for more information about Nardil and how to take it safely.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.