What should I be careful about before taking maprotiline?

There are several things to know and be careful about before taking maprotiline:

  • This medication can result in suicidal thoughts and can trigger extreme anxiety, irritability, aggressiveness, restlessness, panic, hostility, hyperactivity and sleeplessness.
  • While taking this drug, be alert for blurred vision, lightheadedness, dizziness and fainting.
  • Maprotiline can cause dry mouth (chewing sugarless gum and sucking on hard candy can help provide relief).
  • You may need to limit sun exposure (or use sunscreen and wear cover-ups) while taking this medication, as it can increase sun sensitivity.
  • Maprotiline can react with alcohol, tobacco and certain preservatives.
  • Possible drug and herbal interactions with: ziprasidone, cocaine, St. John's Wort, droperidol, sparfloxacin, halofantrine, pimozide, levomethadyl, Carbex, Eldepryl, Marplan, Nardil, Parnate and other medicines for depression. Maprotiline may also react with barbiturates and cimetidine and with medicines for thyroid, high blood pressure, heart arrhythmia, hay fever, colds, allergies, breathing difficulties and sleeping problems.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.