What are the side effects of imipramine pamoate?

Initial dosing can increase thoughts of suicide, especially in people age 24 and younger. Imipramine should not be used to treat children or teenagers younger than 18 years. Common side effects like drowsiness can affect some daily activities. If any of the following side effects are persistent or worsen, talk to your doctor. Common side effects include:  

  • blurred vision
  • constipation or diarrhea
  • decreased sex drive or difficulty having an orgasm
  • drowsiness
  • dizziness
  • dry mouth
  • headache
  • impotence
  • lack of coordination
  • loss of appetite
  • nightmares
  • nausea
  • vomiting
  • ringing in your ears
  • stomach ache
  • swelling of the breasts (men and women)

If any of the following behavioral side effects develop, talk to your doctor right away. Behavioral side effects include:

  • aggression
  • hyperactivity
  • increased thoughts of suicide
  • increased depression
  • insomnia
  • irritability
  • manic behavior
  • panic attack

Although unwanted side effects can be uncomfortable, do not stop taking your medication unless directed to do so by your doctor. Stopping your doses suddenly can cause symptoms of withdrawal. If you have any of the following severe side effects, talk to your doctor right away. Serious side effects include:

  • chest pain
  • confusion or hallucinations
  • change in frequency of urination
  • easy bruising or bleeding
  • feeling short of breath
  • irregular heartbeat (fast, pounding, or uneven)
  • irregular movement of the eyes, tongue, jaw, or neck
  • malaise
  • persistent thirst with headache, nausea, vomiting, and weakness
  • rash
  • sudden weight gain
  • sudden numbness or weakness
  • sudden headache, confusion, blurred vision, speech, or lack of balance

Certain lab tests may be needed to monitor blood sugar levels while using imipramine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.