Does nortriptyline hydrochloride oral solution interact with drugs or food?

Nortriptyline hydrochloride oral solution should not be taken with MAO inhibitors because the combination of the two drugs can lead to life-threatening conditions. Also do not take this medication with arsenic trioxide; irregular heart beat drugs; halofantrine; other drugs for mental depression; phenothiazines such as perphenazine, thioridazine, and chlorpromazine; pimozide; probucol; procarbazine; sparfloxacin; St. John's Wort and ziprasidone.

Other medications that may interact with nortriptyline hydrochloride oral solution include arbutamine; blood thinners like warfarin; disulfiram; levodopa; bronchodilators or decongestants including albuterol, epinephrine, and phenylephrine; stimulants including amphetamines, and illegal street drugs like MDMA/ectasy; thyroid medication; anticholinergic drugs, such as benztropine and belladonna alkaloids; and high blood pressure medication including drugs like clonidine, guanabenz, and reserpine. Other medications that may affect how nortriptyline works include cimetidine; fluconazole; terbinafine; quinidine; propafenone; flecainide; and other antidepressants, including SSRIs like paroxetine; fluoxetine; fluvoxamine.

If you have been taking fluoxetine, you should wait five weeks before beginning to take nortriptyline hydrochloride oral solution. You should tell your doctor if you take any of these medications; your doctor may choose to alter dosages. You should not drink alcohol while taking nortriptyline hydrochloride oral solution. You should tell your doctor about all medications, vitamins, minerals, or supplements that you take prior to beginning nortriptyline HCl.

Continue Learning about Antidepressant

Are Antidepressants Safe to Take During Pregnancy?
Are Antidepressants Safe to Take During Pregnancy?
Research suggests that depression is diagnosed twice as often in women as it is in men, and it typically presents during a woman’s childbearing years....
Read More
How do antidepressant medications affect weight?
Dr. Jack Merendino, MDDr. Jack Merendino, MD
This depends mostly on what medication is being used, but it also varies a great deal from one perso...
More Answers
What should I know before taking doxepin?
Donna Hill Howes, RNDonna Hill Howes, RN
It is not known if doxepin is safe or effective for children and teens under 18 years of age.  If y...
More Answers
What Is Treatment-Resistant Depression?
What Is Treatment-Resistant Depression?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.