How does milnacipran interact with other medications or foods?

Milnacipran may interact with other medications, supplements, and foods. The combination of milnacipran with certain medications may cause an increase, decrease or altered effect of either medication.

Although you should thoroughly discuss with your doctor the potential interactions of all medications you are taking, some medications that are known to interact with milnacipran include the following: anticoagulants; antidepressants; anti-anxiety medications; nonsteroidal anti-inflammatory drugs (NSAIDs); clonidine; clomipramine; digoxin; diuretics; duloxetine; epinephrine; lithium; MAO inhibitor; migraine headache medications; pain medications; seizure medications; selective serotonin reuptake inhibitors (SSRIs); sleeping pills or tranquilizers; thioridazine; venlafaxine; tramadol.

In addition to prescription medications, tell your doctor about any over-the-counter medications you are taking, including aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve and Naprosyn). It is also important to tell your doctor about supplements you take, especially if you take tryptophan or 5-Hydroxytryptophan (5-HTP).

Continue Learning about Antidepressant

What should I know about antidepressants before I take them?
Dr. Darria Gillespie, MDDr. Darria Gillespie, MD
If you take an SRI, you should avoid alcohol. If you have had seizures, an SRI may not be a good op...
More Answers
Can teens take antidepressants for bipolar disorder?
Dr. Michael Roizen, MDDr. Michael Roizen, MD
Yes, and they can be incredibly helpful. However, they are used with extreme caution in children b...
More Answers
Is it safe to take antidepressants during pregnancy?
John Preston, PsyDJohn Preston, PsyD
Most experts agree that some new-generation antidepressants (e.g., Prozac, Zoloft, Effexor, Well...
More Answers
Can antidepressants treat gastrointestinal (GI) disorders?
Lawrence S. Friedman, MDLawrence S. Friedman, MD
If either anxiety or depression appears to be a factor in a functional gastrointestinal (GI) disorde...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.