How does desipramine interact with other medications and food?

Desipramine can interact adversely with a variety of other medications and foods. Some medicines should never be taken with desipramine. These medications include: other antidepressants, amoxapine, heart medicines, arsenic trioxide, levomethadyl, phenothiazines, monoamine oxidase inhibitors (MAOIs), probucol, procarbazine, pimozide, sparfloxacin, halofantrine and St. John's Wort.

Other medications that might interact with desipramine include: anxiety or sleeping medications, barbiturates, heart rhythm medications, allergy medications, atropine, cimetidine, cold and flu medicines, seizures or epilepsy medications and thyroid hormones.

Before taking any medications, you should make a list for your doctor of all of the medications you are currently using. Alcohol, as well as grapefruit and grapefruit products, can also interact with desipramine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.