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How does Cymbalta work to relieve lower back and osteoarthritis pain?

Cymbalta (duloxetine) can relieve lower back and osteoarthritis pain by increasing the amounts of two chemicals in the brain—serotonin and norepinephrine. This helps to block pain signals. Cymbalta belongs to a class of drugs known as selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which are used to treat depression.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.