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What should I know about clomipramine before taking it?

Clomipramine is not a cure for obsessive-compulsive disorder (OCD). However, this drug appears to help people with OCD manage their symptoms, which can include persistent anxiety-provoking thoughts and a compulsion to repeat certain behaviors, such as hand washing or checking door locks. Scientists believe that clomipramine helps relieve OCD symptoms by increasing a brain chemical called seratonin.

Do not use this medication if you have recently had a heart attack or if you have used an MAO inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam) or tranylcypromine (Parnate) within the past 14 days.  You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years of age. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.