Nefazodone (Serzone) is an antidepressant used to treat major depressive disorders. It is a phenylpiperazine-derivative antidepressant that acts in a different way than other antidepressants. As with all medicines, the benefits of taking a drug during pregnancy must outweigh the risks for both mother and baby.
Nefazodone has been assigned to Pregnancy Category C by the FDA, which means animal studies indicate a problem. But this has not been studied in humans. So its use during pregnancy should be approached with caution since there are no studies confirming the safety during pregnancy.
Nefazodone carries many safety warnings in both adults and children that apply to other antidepressants as well. In addition to side effects, a Black-Box Warning alerts users to the potential for liver toxicity, worsening of depressive symptoms and thoughts of suicide.
Tell your doctor if you have become pregnant or planning on becoming pregnant because there may be another option.
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.