Can Remeron interact with other medications or foods?

The antidepressant Remeron (mirtazapine) may interact with many medications and with alcohol but is not known to interact with foods. Before you start taking Remeron, tell your doctor about all medicines (prescription and nonprescription), supplements and herbal remedies you take. Once you begin Remeron, do not take any new medication or supplement without talking to your doctor first.

While using Remeron, you should not take medicines known as monoamine oxidase inhibitors (MAOIs), or any amino acid supplements containing tryptophan, because these can cause a life-threatening condition called serotonin syndrome. For the same reason, you should also avoid triptan medicines (typically prescribed to treat migraines), St. John's wort, the pain medication Tramadol, selective serotonin reuptake inhibitors (SSRIs) and a number of other drugs used to treat mental illnesses. Other medicines, including phenytoin, carbamazepine, cimetidine, ketoconazole, paroxetine, amitriptyline, erythromycin and warfarin, may require dosage adjustments because Remeron can affect how quickly they're absorbed.

While you're on Remeron, you should also avoid drinking alcohol or using the medicine diazepam (Valium). This is because Remeron can make you drowsy and affect your motor skills, and alcohol or diazepam will worsen this reaction.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.