Who should not take Sabril?

You should not take Sabril (vigabatrin) if you have a history of vision problems or have had an allergic reaction to Sabril. Those with a history of kidney disease should tell their doctor, as it may cause the medication to remain in the system longer. People with a history of mood disorders must take extra precautions, as Sabril could make mood disorders worse and there is a risk for suicidal tendencies when on Sabril. Doses may need to be adjusted or discontinued. If you have anemia or a history of substance abuse, talk to your doctor. In some people, Sabril makes seizures worse. It is best to avoid breast-feeding and pregnancy while on Sabril. While powder forms of Sabril are used to treat infants with infantile spasms, testing has been limited.